The Effects of the Allergen Mala s 11, from the Opportunistic Yeast Malassezia, on Antigen Presenting Cells
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منابع مشابه
Structural and Functional Studies of Malassezia Sympodialis-derived Allergens
Atopic eczema (AE) is a chronic inflammatory skin disease characterised by pruritic (itchy) skin lesions. The pathogenic mechanisms underlying AE are still unclear, although several factors such as genetic predisposition, a dysfunctional skin barrier, exposure to environmental allergens and skin colonisation with microorganisms appear to be of importance. Malassezia sympodialis is a yeast which...
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Abstract Background and Objective: Malassezia yeast is considered lipophilic normal flora of human skin and warm-blooded vertebrates. This fungus is an opportunistic pathogen in causing seborrheic dermatitis. In this study, the yeasts isolated from the crust of the patients with seborrheic dermatitis were identified by PCR-Sequencing. Material and Methods: In this study, 65 ...
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We have identified thioredoxins (Trx) of Malassezia sympodialis, a yeast involved in the pathogenesis of atopic eczema, and of Aspergillus fumigatus, a fungus involved in pulmonary complications, as novel IgE-binding proteins. We show that these Trx, including the human enzyme, represent cross-reactive structures recognized by serum IgE from individuals sensitized to M. sympodialis Trx. Moreove...
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Atopic eczema (AE) is a chronic inflammatory skin disease, characterized by intense itching, dry skin, infiltration of immune cells and skin lesions. To date, the cause of AE, a disease affecting 15-30% of children and 210% of adults, remains unknown and the pathomechanisms are not fully understood. Many factors, however, have been implied to contribute to this complex disorder, such as genetic...
متن کاملRapid Identification of Malassezia furfur from other Malassezia Species: A Major Causative Agent of Pityriasis Versicolor
The present study is designed to evaluate the application of a simple method for rapid identification of Malassezia furfur among other Malassezia spp. based on production of a brownish-red pigment and its diffusion into the medium containing L-tryptophan as a sigle source of nitrogen. 91 strains of Malassezia (20% M. furfur, 2% M. sympodialis, 5% M. obtosa and 73% M. globosa) isolated from ski...
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